A.  Contributions to books

(1) Ezike AC (2012). Urinary Tract Infections. In: Therapeutic basis of Clinical Pharmacy in the tropics. Aguwa CN (Ed), 4^th Edition pp 178-193.

(2) Ezike AC (2012). Filarial diseases, In: Therapeutic basis of Clinical Pharmacy Practice in the tropics. Aguwa CN (Ed), 4^th Edition pp 302-319.

(3) Akah PA, Ezike AC (2012). Prospects for development of new antiviral, antitumor and cytotoxic drugs from medicinal plants inhibitors of α-glucosidase. In: Contemporary Issues in Ethnopharmacology, Okoli CO, (Editor), Research Signpost, India pp 157 - 178.

(4) Ezike AC, Okoli CO (2012). Reducing complications of diabetes mellitus with medicinal plants: Inhibitors of aldose reductase and advanced glycation end products. In: Contemporary Issues in Ethnopharmacology, Okoli CO, (Editor), Research Signpost, India pp 125 - 156.

(5) Okoli CO, Ezike AC (2012). Medicinal Plants inhibitors of carbohydrate metabolizing enzymes: Potentials in the management of diabetes mellitus. In: Contemporary Issues in Ethnopharmacology, Okoli CO, (Editor), Research Signpost, India pp 53 - 124.

(6) Ezike AC, Akah PA. 2010. Antiasthmatic medicinal plants. In: Comprehensive Bioactive Natural Products Vol 3: 189 – 227. Efficacy, Safety & Clinical Evaluation (Part-2) V. K. Gupta (Ed) Chapter 9.

(7) Okoli CO, Akah PA, Ezike, AC, Udegbunam S, Nworu CS, Okoye TC (2008). The Ethnobiology and Pharmacology of Jatropha curcas L. In: Principles and Practice of Ethnomedicine (African Approach), Akah, P.A. (Editor), Research Signpost: India. Available online at www.ressignpost.com

(8) Okoli CO, Njoku OU, Ononugbu IC, Ezike AC. (2008). Medicinal plants and antioxidant activity. In: Principles and Practice of Ethnomedicine (African Approach), Akah, P.A. (Editor), Research Signpost: 37/661, Kerala, India. Available online at www.ressignpost.com

(9) Okoli CO, Akah PA, Okoye TC, Ezike AC. (2008). Behavioural effects of medicinal plants. In: Principles and Practice of Ethnomedicine (African Approach), Akah, P.A. (Editor), Research Signpost 37/661, Kerala, India. Available online at www.ressignpost.com

B.  Journal articles

(1) Ezike AC, Orji CH, Ochiogu IS, Ndu OO, Mbaoji FN, Akah PA. 2016. Effects of sub-chronic oral intake of Hibiscus sabdariffa calyx extract on some reproductive indices in adult male rats. African Journal of Pharmaceutical Research and Development, 8(1): 66-72.

(2) Ezike AC, Okonkwo CH, Akah PA_, Okoye TC_, Nworu CS, Mbaoji FN, Nwabunike IA, Onyeto CA. 2016. Landolphia owariensis leaf extracts reduce parasitemia in Plasmodium berghei infected mice, Pharmaceutical Biology, 54(10): 2017 – 2025.

(3) Ezike AC, Ufere IK, Akah PA, Ezea S, Okoli CO. 2016.  Extracts of Leptadenia hastata leaf, a famine food and traditional remedy for furuncles, suppress inflammation in murine models. Journal of Dietary Supplements, 13 (2): 119-135.

(4) Mbaoji FN, Ezike AC, Nworu CS, Onyeto CA, Nwabunike IA, Okoli IC, Akah PA. 2016. Antioxidant and hepatoprotective potentials of Stemonocoleus micranthus Harms. (Fabaceae) stem bark extract. International Journal of Pharmacy and Pharmaceutical Sciences, 8(7): 47-51.

(5) Ezike AC, Onyeto CA, Nwabunike IA, Mbaoji FN, Attah BE, Amanambu SO, Okoli CO. 2015. Antiinflammatory activity of Buchholzia coriacea (Capparaceae) leaf extract: Evaluation of components of the inflammatory response involved. Journal of Complementary and Integrative Medicine, 12 (2): 153 – 158.

(6) Ezike AC, Akah PA, Udegbunam SO, Igboeme S,  Ibe C, Ezeike C, Emedo H. 2015. Potentials of Bridelia ferruginea stem bark extracts in wound care. Journal of Chemical and Pharmaceutical Research. 7 (1) 917-925.

(7) Okoye TC, Akah PA, Ezike AC, Uzor PF, Odoh UE, Igboeme SO, Onwuka UB, Okafor SN. 2014. Immunomodulatory effects of Stachytarpheta cayennensis leaf extract and its synergistic effect with artesunate. BMC Complementary and Alternative Medicine 2014, 14:376.

(8) Nwabunike IA, Ezike AC, Nwodo NJ, Udegbunam SU, Okoli CO. 2014. Bioactivity-guided studies on the antiinflammatory activity of extract of aerial parts of Schwenckia americana L. (Solanaceae). Journal of Medicinal Plants Research, 8(22): 794-801.

(9) Mbaoji FN, Okoli CO, Ezike AC. 2014. Preliminary antihyperglycemic activity-guided studies on the leaf extract and fractions of Ocimum basilicum L. Journal of Chemical and Pharmaceutical Research, 6 (4) 575 – 580.

(10) Ezike AC, Akah PA, Okoli CO, Ufere IK, Ezeudu E, Okoye CF, Ashara C, Igbokwe IN.2014. Studies on gastrointestinal effects of Desmodium velutinum: A traditional remedy for diarrhea. American Journal of Pharmacology and Toxicology, 9 (2): 114-124.

(11) Okoye TC, Akah PA, Nworu CS, Ezike AC. 2014. Kaurenoic acid isolated from the root bark of Annona senegalensis induces cytotoxic and antiproliferative effects against PANC-1 and HeLa cells. European Journal of Medicinal Plants, 4 (5): 579-589.

(12) Okoli CO, Nwezza AC, Ezike AC. 2014. Extracts of Phyllanthus niruri aerial parts suppress acute and chronic inflammation in murine models. Journal of Herbs, Spices and Medicinal Plants, 20 (3): 256-268.

(13) Ezike AC, Akah PA, Okoli CO, Okoye TC, Ogbu OM, Okonkwo I, Uwakwe G, Ibe S, Ezema V. 2013. Studies on the antiinflammatory, antinociceptive and antimicrobial activities of Combretum calobotrys (Combretaceae) leaf.  Journal of Medicinal Plant research, 7(21): 1568-1576.

(14) Ezike AC, Akah PA, Okore VC, Okoli CO, Okoye TC, Okoye AC. 2013. In vitro evaluation of the anthelmintic and antibacterial activities of three Nigerian medicinal plants. BioMed Rx, 1(3): 254-257.

(15) Ukekwe IF, Akah PA, Ezike AC, Okoli CO. 2013. Assessment of the sub-acute and delayed toxicity of artemether-lumefantrine combination in rats. International Journal of Research in Ayurveda and Pharmacy.  4(2): 168-176.  

(16) Okoye TC, Akah PA, Ilogu CL, Ezike AC, Onyeto CA. 2012. Anti-diabetic effects of methanol extract of the seeds of Buchholzia coriacea and its synergistic effects with metformin. Asian Journal of Biomedical and Pharmaceutical Sciences 2(12) 2012, 32-36.

(17) Okoli CO, Mamah CC, Ubaka CM, Ezike AC, Akah PA.2012. Efficacy of artemether-lumefantrine combination in rural Nigeria. The Journal of Applied Research in Clinical and Experimental Therapeutics 12 (1): 14-20.

(18) Okoye TC, Akah PA, Okoli CO, Ezike AC, Omeje EO, Odoh UE. 2012. Antimicrobial effects of a lipophilic fraction and kaurenoic acid isolated from the root bark extracts of Annona senegalensis. Evidence-Based Complementary and Alternative Medicine, Volume 2012, Article ID 831327, 10 pages, doi:10.1155/2012/831327.

(19) Okoye TC, Akah PA, Ezike AC, Okoye MO, Onyeto CA, Ndukwu F, Ohaegbulam E, Ikele L. 2012. Evaluation of the acute and sub-acute toxicity of Annona senegalensis root bark extracts. Asian Pacific Journal of Tropical medicine, (2012): 277-282.

(20) Ezike A, Ebi G, Akah P, Okeudo U. 2011. Evaluation of antibacterial activity of leaf and stem extracts of Combretum calobotrys. Journal of Chemical and Pharmaceutical Research, 3(3):676-679.

(21) Okoye TC, Akah PA, Ezike, AC, Nwoye JC. 2011.  Studies on the effects of Annona senegalensis root bark extract on acute and chronic inflammation in rats. Journal of Pharmacy Research 2011, 4(5): 1443 - 1444.

(22) Ezike AC, Akah PA, Nnamani EM, Okoli CO, Ojike FU, Eze FS, Chime CE, Azosiri IJ. 2011. Studies on the antiulcer and gastrointestinal effects of stem bark extract of Bridelia ferruginea Journal of Complementary and Integrative medicine, Vol. 8 (1): Article 27. DOI:10.2202/1553-3840.1507.  

(23) Ezike AC, Akah PA, Okoli CO, Udemezue N, Okoro O. 2011. Experimental evaluation of antiulcer and spasmolytic potentials of leaves of Cajanus cajan Natural Products: An Indian Journal Vol 7, Issue 1, 2011.

(24) Okoli CO, Obidike IC, Ezike AC, Akah PA, Salawu OA. 2011. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. Pharmaceutical Biology, 2011; 49(3): 248–255.  DOI: 10.3109/13880209.2010.501456

(25) Okoye TC,  Akah PA,  Okoli CO, Ndu OO, Ezike AC, Okoye MO, Mbaoji FN and Agba EU. 2010. Anti-diarrhoeal and antispasmodic effects of leaf extract of Pterocarpus santalinoides Nigerian Journal of Pharmaceutical Research, 8 (1): 138 - 144.

(26) Ezike AC, Akah PA, Okoli CO, Udegbunam S, Okwume N, Okeke C, Iloani O. 2010. Medicinal plants used in wound care: A study of Prosopis africana (Fabaceae) stem bark. Indian Journal of Pharmaceutical Sciences, 72 (3): 334 - 339.

(27) Nwonu P, Okoye TC, Akah PA, Ezike AC, Ejindu IA, Eneh SE. 2010. Wound healing properties of stem bark extract of Tabebuia rosea.  Journal of Pharmaceutical and Allied Sciences, , 7 (4): 1115 – 1120.

(28) Okoli CO, Onyeto CA, Akpa BP, Ezike AC, Akah PA, Okoye TC. 2010.  Neuropharmacological evaluation of Annona senegalensis leaves. African Journal of Biotechnology Vol. 9(49): 8435-8444.

(29) Okoli CO, Ugwu EC, Ubaka CM, Ezike AC, Akah PA. 2010. Efficacy of artesunate-amodiaquine combination therapy for uncomplicated malaria in south-eastern Nigeria. The Journal of Applied Research in Clinical and Experimental Therapeutics 10 (1): 17-23.

(30) Ezike AC, Akah PA, Okoli CO, Okpala C. 2010. Experimental evidence for the antidabetic activity of Cajanus cajan leaves in rats. Journal of Basic and Clinical Pharmacy.1 (2): 81 - 84

(31) Okoli CO, Akah PA, Ezike AC 2010. Effects of Culcasia scandens leaf extracts on chronic inflammation and specific cell-mediated immune response. Journal of Tropical Medicinal Plants, 10 (2): 163 – 166. 

(32) Okoye TC, Akah PA, Okoli CO, Ezike AC, Mbaoji FN. 2010. Antimicrobial and antispasmodic activity of leaf extract and fractions of Stachytarpheta cayennensis Asian Pacific Journal of Tropical Medicine 3 (1):189 - 192.

(33) Okoli CO, Ezike AC, Agwagah OC, Akah PA. 2010. Anti-convulsant and anxiolytic evaluation of leaf extracts of Ocimum gratissimum, a culinary herb. Pharmacognosy Research, 2 (1): 33 – 37. 

(34) Okoli CO, Ibiam AF, Ezike AC, Akah PA and Okoye TC 2010. Evaluation of antidiabetic potentials of Phyllanthus niruri in alloxan diabetic rats. African Journal of Biotechnology, 9(2):248 – 259.

(35) Okoli CO, Ezike AC, Akah PA, Udegbunam SO, Okoye TC, Mbanu TP, Ugwu E. 2009. Studies on wound healing and antiulcer activities of extract of aerial parts of Phyllanthus niruri L. (Euphorbiaceae). American Journal of Pharmacology and Toxicology, 4(4): 118-126.

(36) Akah PA, Ezike A.C, Offiah N, Agbata CA. 2009. Evaluation of the acute toxicity of Corexit 9527/Forcados crude oil mixture on Tilapia guineensis and Sarothedron melanotheron. Sustainable Human Development Review. 1 (4): 157 – 178.

(37) Ezike AC, Akah, PA, Okoli CO, Ezeuchenne NA, Ezeugwu S. 2009. Carica papaya (paw-paw) unripe fruit may be beneficial in ulcer. Journal of Medicinal Food 12 (6): 1268–1273.

(38) Aguwa CN, Ejiekpe N, Okoli CO, Ezike AC. 2009. Pilot studies on the anti-inflammatory activity of leaf extracts of Buchholzia coriacea  Engl  (Capparidaceae). Natural Products: An Indian Journal, 5(3): 98 – 103.

(39) Akah PA, Okolo CE, Ezike AC. 2009.The haematinic activity of the methanol leaf extract of Brillantasia nitens Lindau (Acanthaceae) in rats. African Journal of Biotechnology, 8(10): 2389-2399.

(40) Nworu CS, Akah PA, Ndu OO, Ezike AC, Onyekwelu, NI. (2008) Pharmacokinetic evaluation of drug interactions between co-trimoxazole and zidovudine in rabbits. International Journal of Tropical Medicine 3(2): 30-35.

(41)  Ezike AC, Akah PA, Okoli CO. 2008. Bronchospasmolytic activity of the extract and fractions of Asystasia gangetica leaves. International Journal of Applied Research in Natural Products 1(3): 8 – 13.

(42) Akah PA, Nnaeto O, Nworu CS, Ezike AC. (2007) Medicinal plants used in the traditional treatment of peptic ulcer diseases: a case study of Napoleona vogelii Hook and Planch (Lecythidaceae). Research Journal of Pharmacology 1 (3): 67-74.

(43) Akah PA, Ezike AC, Nwafor SV, Okoli CO. Enwerem N.M. (2003) Evaluation of the antiasthmatic property of Asystasia gangetica leaf extracts. Journal of Ethnopharmacology, 89: 25-36.